Non-Invasive Prenatal Testing (NIPT)
It is genetic test offered during pregnancy to find the risk for having a chromosomal disorder like Down syndrome (trisomy 21), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). Moreover, this test can also determine the sex of the fetus. It’s done by taking a peripheral blood samples of pregnant woman at 10th week of pregnancy which contains fragments of DNA from the fetus. This test estimates the likelihood of the fetus having a particular genetic syndrome.
1. NIFTY® Test (Non-Invasive Fetal TrisomY Test)
The NIFTY® Test offers screening for some of the most common trisomies present at birth, including
- Trisomy 21 (Down Syndrome),
- Trisomy 18 (Edwards Syndrome) and
- Trisomy 13 (Patau Syndrome).
NIFTY® also provides testing options for sex chromosomal aneuploidies, chromosomal deletions /duplications and gender. NIFTY® was the first NIPT to enter clinical testing in 2010 and has been validated by a study on nearly 147,000 pregnancies. More than 11,520,000 NIFTY tests have been carried out worldwide. NIFTY® Test may also be used to test;
- Twin Pregnancy (trisomies 21, 18 and 13)
- IVF Pregnancy Egg Donor Pregnancy
Sex Chromosome Aneuploidies: Monosomy X (Turner Syndrome), XXY (Klinefelter Syndrome), XXX (Triple-X Syndrome), XYY (Jacobs syndrome), Sex Indication, Y Chromosome detection.
Why is NIFTY done?
Noninvasive prenatal testing helps determine the fetus’s chances of being born with certain chromosomal disorders. Suitable for pregnant mothers if;
- Have a child with a chromosomal abnormality.
- Have had an ultrasound that shows that the fetus may have an abnormality.
- Have had an earlier screening test that suggests a potential problem.
