Genetic Research Publications ELC Biogen Pakistan

Publications

Research Findings & Scientific Publications

ELC Biogen’s team of geneticists and researchers regularly contributes to peer-reviewed literature, sharing insights from our diagnostic and research programs with the broader scientific and clinical community.

Prevalence of Transfusion-Transmitted Infections in Multiple Blood Transfusion-Dependent Thalassemic Patients in Asia: A Systematic Review

First published online April 22, 2022

Thalassemia is a genetic blood disorder that affects the production of hemoglobin, the protein in red blood cells responsible for carrying oxygen. Patients with severe forms of the condition require regular blood transfusions to survive, but repeated transfusions can expose them to serious infections such as hepatitis B, hepatitis C, and HIV when donor blood is not properly screened.

Our systematic review examined the risk of these transfusion-transmitted infections (TTIs) among thalassemia patients across Asia. The findings show that hepatitis C is the most prevalent infection in this population, followed by hepatitis B and HIV — underscoring the need for more rigorous screening protocols and stricter transfusion safety standards.

Hepatitis C is the most prevalent transfusion-transmitted infection among thalassemia patients in Asia
Stricter donor blood screening significantly reduces transmission risk
Carrier screening enables early identification and informed family planning
Improved transfusion safety protocols protect long-term patient health

Our Commitment to Research

ELC Biogen’s scientists continue to collaborate with academic and clinical partners on studies spanning hereditary cancer genetics, reproductive health, and infectious disease screening. Additional publications from our team will be featured here as they are released.